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Vol.38 No.5 contents | Japanese/English |
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Full Text of PDF (378K) Article in Japanese |
Detection of Antimicrobial-Resistant Organisms (AMROs) and Related Factors for AMROs Colonization in Long-term Care Facilities
Masamichi OGURA1), Satomi ASAI2), Kazuo UMEZAWA3), Toshio OHSHIMA4), Toshiki KAJIHARA5), Koji YAHARA5) and Motoyuki SUGAI5)
1)Department of Nursing, School of Medicine, Tokai University, 2)Department of Laboratory Medicine, School of Medicine, Tokai University, 3)Department of Emergency and Critical Care Medicine, School of Medicine, Tokai University, 4)Department of Laboratory Medicine, Nitobebunka College, 5)Antimicrobial Resistance Research Center, National Institute of Infectious Diseases
This study aimed to develop appropriate measures against drug-resistant bacteria for elderly people living in long-term care facilities. The stool samples of facilities A-C were analyzed via a survey on extended-spectrum beta-lactamase (ESBL)-producing bacteria carriage. Factors related to carriage, user characteristics, and facility characteristics were also analyzed. The results showed that the detection rate of ESBL-producing bacteria was significantly higher in the antibacterial drug administration group (detection rate ratio of 12.71 [95%CI: 1.33-121.53]), indicating a relationship between ESBL-producing bacteria carriage and antibiotics usage history. Moreover, the detection rate was highest (36.7%) in elderly living in unit-type (private room) facility (facility B) with the lowest degree of care. The detection rate was lowest (5.9%) in the conventional (multi-bed room type) facility (facility C) with a high level of nursing care. The key difference between the two facilities was that some users were prescribed antibiotics daily in facility B while no antibiotics were prescribed at all in facility C. It was once thought that nursing homes for the elderly play a major role in spreading drug-resistant bacteria. However, the results of this study suggest that the risk of drug-resistant bacteria carriage varies greatly depending on the frequency of antibiotics prescription.
Key words：long-term care facilities, extended-spectrum β-lactamase (ESBL)-producing bacteria, degree of care, antibiotics
e-mail: mogura＠tokai-u.jp
Received: March 31, 2023
Accepted: July 22, 2023
38 (5)：229─234,2023
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