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Vol.35 No.4 contents | Japanese/English |
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Full Text of PDF (326K) Article in Japanese |
Impact of an Antimicrobial Stewardship Pharmacist's Intervention on Blood Culture-positive Patients
Yasuhiro SASAKI1)6), Misato AMANO1)6), Ayumi KANAMARU2)6), Akiko YAMAKUCHI3)6), Hirobumi TAKAYASU4)6) and Masataka YANO5)6)
1)Department of Pharmacy, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 2)Department of Nursing, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 3)Department of Microbiological Laboratory, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 4)Department of Pediatrics, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 5)Department of Urology, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 6)Antimicrobial Stewardship Team, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation
In March 2018, an antimicrobial stewardship (AS) team commenced an active intervention in patients with bacteremia at the Tama-Nanbu Chiiki Hospital, Japan. An AS pharmacist audited and reviewed the prescription of antimicrobial agents in patient with bacteremia and suggested empirical and definitive changes to the antimicrobials. A total of 247 patients were evaluated, which resulted in 102 interventions, with 88% acceptance rate. The rate of appropriate de-escalation rose from 55% to 79% (p < 0.05).
Although the total consumption of antimicrobial agents did not markedly change the observation period, the use of broad-spectrum antibiotics such as tazobactam/piperacillin was significantly decreased. It was concluded that the activities of the AS team are important as they lead to proper selection of antimicrobial drug therapy.
Key words：antimicrobial stewardship program, bacteremia, de-escalation
e-mail: yasuhiro_sasaki1＠tokyo-hmt.jp
Received: November 8, 2019
Accepted: April 20, 2020
35 (4)：157─162,2020
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