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Article in Japanese

Survey of Antibiotic Therapy for Surgical Site Infection after Mandibular Wisdom Tooth Extraction

Chie SAITO1), Kensuke YOSHIDA1)2), Shota KANEKO1), Hirokazu ISOBE1)3) and Yasumitsu KODAMA2)
1)Division of Hospital Pharmacy, Niigata University Medical and Dental Hospital, 2)Division of Oral and Maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Sciences, 3)Division of Infection Control and Prevention, Niigata University Medical and Dental Hospital


There are no guidelines for surgical site infection (SSI) antibiotic therapy; however, The Japanese Association for Infectious Diseases/Japanese Society of Chemotherapy's Guide to Clinical Management of Infectious Diseases 2019 (hereon referred to as guidelines) indicate recommended antibiotic therapy and administration period for dental infections. Therefore, we retrospectively investigated antibiotic therapy for SSI after mandibular wisdom tooth extraction with reference to the guidelines. We retrospectively investigated patients with SSI after mandibular wisdom tooth extraction at the dental outpatient clinic during January 2015-December 2019 for the type of antibiotic therapy, dosage of amoxicillin (AMPC), administration period, and presence or absence of bacterial test. We found that SSI occurred in 1.6% (96/5,940) cases; AMPC was gradually increased and selected in 70.4% (19/27) cases of SSI antibiotic therapy in 2019. The dose was 250 mg per dose in almost of the selected AMPC, administration period was four days, and bacterial tests were performed in 11.5% (11/96) cases. According to the guidelines, a dosage of 500-mg AMPC is recommended for SSI with drainage, but all of the above cases selected half of the dose. Therefore, the duration of antibiotic therapy for SSI was in accordance with the guidelines. Further, we considered that the choice of antibiotics, a single dose of AMPC, and the presence or absence of bacterial test needed to be improved.

Key words:mandibular wisdom tooth extraction, surgical site infection (SSI), antibiotic therapy, dental outpatient clinic, antibacterial management

e-mail: chiesai.lc6@nuh.niigata-u.ac.jp

Received: August 12, 2021
Accepted: December 23, 2021

37 (2):62─68,2022

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