Japanese Society for Infection Prevention and Control-Online Journal

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Healing Process of a Skin Wound in Rat Using Deep UV Treatment

Kazuo KAWASAKI, Toshikatsu FUNAYAMA and Koichi YAMAMOTO
Graduate School of Medicine, Osaka University

This study's final purpose is applying deep-UV treatment, which has strong bactericidal effects. In this paper, we investigated the bactericidal effect of deep UV in near field to organism as one of the methods. We comparatively reviewed data pertaining to deep UV exposure of a rat wound infected with Escherichia coli. As a result, it was observed that 90% killing of E. coli could be attained by exposure to 670 mJ/cm² of deep UV, and there were no adverse effects on the rat's skin wound. From this, it was found that despite exposure to doses which have bactericidal effect on E. coli, there were no adverse effects to the rat's wound. In the present study, design engineers understood new engineering technology and considered its medical application with a medical scientist and conducted the experimental tests.

Key words：deep-UV, evanescent field, design, sterilization, consilience

e-mail: funayama＠sahs.med.osaka-u.ac.jp

Received: August 10, 2016
Accepted: September 14, 2017

32 (6)：355─363,2017