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Vol.32 No.6 contents | Japanese/English |
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Full Text of PDF (300K) Article in Japanese |
Impact of an Antimicrobial Stewardship Program Introduced by Pharmacist
Yasuhiro SASAKI1), Ayumi KANAMARU2), Akiko YAMAKUCHI3) and Masataka YANO4)
1)Department of Pharmacy, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 2)Department of Nursing, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 3)Department of Pathology, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation, 4)Department of Urology, Tama-Nanbu Chiiki Hospital, Tokyo Metropolitan Health and Medical Treatment Corporation
Antimicrobial stewardship programs (ASPs) are essential to optimize the prescription of antibiotics. In this study, we introduced restriction of 4th cephems and prospective audit of carbapenems. The days of therapy per 1000 patient-days of 4th cephems significantly decreased from 51.87 to 28.09 after restriction of 4th cephems, and those of carbapenems significantly decreased from 9.35 to 3.80 after prospective audit of carbapenems. All antibiotic costs were reduced by 400,000 yen (18%) monthly. The susceptibility of Pseudomonas aeruginosa showed no difference between the pre- and post-introduction. A hospital policy to optimize antimicrobial prescription introduced by pharmacist decreased the days of therapy per 1000 patient-days of 4th cephems and carbapenems and antibiotic costs.
Key words：antimicrobial use density, carbapenems, antimicrobial stewardship program
e-mail: yasuhiro_sasaki1＠tokyo-hmt.jp
Received: March 3, 2017
Accepted: August 4, 2017
32 (6)：369─373,2017
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