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Antimicrobial Therapeutic Drug Monitoring Performance Rate in Niigata: Evaluation between Performance Rate and Relevant Factors

Hiroki KATAGIRI1), Satoru MITSUBOSHI1), Hikaru KATAGIRI2) and Masami TSUGITA3)
1)Department of Pharmacy, Kaetsu Hospital, 2)Department of Pharmacy, Nigata City General Hospital, 3)Department of Clinical Pharmacy, Niigata University of Pharmacy and Applied Life Sciences


To determine the performance rate of antimicrobial therapeutic drug monitoring (TDM) in Niigata, we conducted a questionnaire survey from June to July 2015. Responses were obtained from 103 out of 125 facilities. TDM performance rate was found to be significantly increased compared to the TDM performance rate as reported in our previous questionnaire survey conducted in 2007 (from 41% in 2007 to 70% in 2015). The centers with a significantly increased rate had an infection control team. In multivariable analysis, board-certified pharmacists and infection control nurses were significantly positively associated with vancomycin TDM performance. Only board-certified pharmacists were significantly positively associated with teicoplanin and arbekacin TDM performance. Overall, our results revealed the change in antimicrobial TDM performance rate from 2007 to 2015 in Niigata. Moreover, we found that board-certified pharmacists are important for antimicrobial TDM performance. Cooperation and support from infection control teams and infection control nurses are necessary to increase antimicrobial TDM performance.

Key words:therapeutic drug monitoring, performance rate, questionnaire survey, board-certified pharmacist

e-mail: k.hiro.n22@gmail.com

Received: July 27, 2017
Accepted: December 5, 2017

33 (2):62─66,2018

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