Journal

The Japanese journal of neuropsychology

[Vol.27 No.1 contents]
Japanese/English

Full Text of this Article
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ArticleTitle Quantitative MRI analysis of gray and white matter structure
Language J
AuthorList Jun Miyata
Affiliation Department of Neuropsychiatry, Kyoto University Hospital
Publication Japanese Journal of Neuropsychology: 27 (1), 47-53, 2011
Received
Accepted
Abstract MRI-based Quantitative analysis methods for brain structure were reviewed. Region of interest (ROI) method and voxel-based morphometry (VBM) are used to measure gray matter volume. The former measures the volume of certain structure manually, and the latter measures the volume voxel by voxel computationally. These methods are complementary. Diffusion tensor imaging (DTI) is sensitive for subtle abnormality of white matter microstructure. DTI derived tractography reconstructs the neuronal fiber tract virtually, and VBM type voxelwise whole brain analysis can also be applied to DTI data. Combination of these quantitative analysis methods for gray and white matter can contribute to reveal the nature of neuropsychiatric diseases in terms of abnormal connectivity of network.
Keywords gray matter, white matter, Region of Interest, voxel-based morphometry, diffusion tensor imaging

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