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[Vol.27 No.1 contents]
Japanese/English
Full Text of this Articlein Japanese PDF (873K) |
| ArticleTitle | Quantitative MRI analysis of gray and white matter structure |
| Language | J |
| AuthorList | Jun Miyata |
| Affiliation | Department of Neuropsychiatry, Kyoto University Hospital |
| Publication | Japanese Journal of Neuropsychology: 27 (1), 47-53, 2011 |
| Received | |
| Accepted | |
| Abstract | MRI-based Quantitative analysis methods for brain structure were reviewed. Region of interest (ROI) method and voxel-based morphometry (VBM) are used to measure gray matter volume. The former measures the volume of certain structure manually, and the latter measures the volume voxel by voxel computationally. These methods are complementary. Diffusion tensor imaging (DTI) is sensitive for subtle abnormality of white matter microstructure. DTI derived tractography reconstructs the neuronal fiber tract virtually, and VBM type voxelwise whole brain analysis can also be applied to DTI data. Combination of these quantitative analysis methods for gray and white matter can contribute to reveal the nature of neuropsychiatric diseases in terms of abnormal connectivity of network. |
| Keywords | gray matter, white matter, Region of Interest, voxel-based morphometry, diffusion tensor imaging |
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