|
[Vol.33 No.2 contents]
Japanese/English
Full Text of this Articlein Japanese PDF (422K) |
| ArticleTitle | Delusional misidentification in Alzheimer's disease and dementia with Lewy bodies: a consecutive patient study |
| Language | J |
| AuthorList | Miho Annaka1), Azusa Kato1), Takuya Sato2), Toru Imamura1)3) |
| Affiliation |
1)Department of Speech Therapy, School of Health Sciences, Niigata University of Health and Welfare 2)Division of Speech Therapy, Department of Rehabilitation, Niigata Rehabilitation Hospital 3)Department of Neurology, Niigata Rehabilitation Hospital |
| Publication | Japanese Journal of Neuropsychology: 33 (2), 142-153, 2017 |
| Received | May 20, 2016 |
| Accepted | Oct 24, 2016 |
| Abstract | Objective: To compare the prevalence and characteristics of delusional misidentification between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) in the consecutive patients at a memory clinic. Subjects: A total of 347 consecutive patients with AD (291 patients) or DLB (56 patients) who presented to our memory clinic for the first time. Methods: We questioned a patient's informant(s) about the details of the patient's delusion in a Neuropsychiatric Inventory (NPI) interview and recorded them word for word. We retrospectively evaluated whether the delusions in each patient fell under the 16 categories of misidentification and delusion, and compared the frequencies for each category. After factor analyses which delineated 2 factors (misidentification and paramnesia) both in AD and DLB, we examined disease and cognitive characteristics between the patient groups with and without each of the 4 factors. Results: In AD patients, the frequencies of most symptoms of delusional misidentification were less than 3%. In DLB patients, frequencies of many symptoms were significantly higher than those in AD patients, and the frequencies of misidentification of people, misidentification of place and belief that absent relatives are in the house were more than 15%. The performance on the word recall task was significantly worse in patients whose delusions fell under misidentification factor and paramnesia factor both in AD and DLB. Discussion: In the consecutive cases of mild to moderate cognitive disorder, DLB was characterized by delusional misidentification. Recent memory deficit may be a common basis of delusional misidentification in AD and DLB. |
| Keywords | delusional misidentification, dementia with Lewy bodies (DLB), Alzheimer's disease, recent memory deficit, frontal lobe dysfunction |
Copyright © 2002 NEUROPSYCHOLOGY ASSOCIATION OF JAPAN All rights reserved
http://www.neuropsychology.gr.jp/