|
The Japanese journal of neuropsychology
|
|
Full Text of this Article
in Japanese PDF (1630K)
|
ArticleTitle
|
Dementia and cognitive reserve |
Language |
J |
AuthorList |
Hiroshi Yoshizawa |
Affiliation |
Department of Neurology, Neurological Institute, Tokyo Women's Medical University |
Publication |
Japanese Journal of Neuropsychology: 34 (2), 142-154, 2018 |
Received |
|
Accepted |
|
Abstract |
The age-related decline of cognitive function is not homogeneous; vocabulary knowledge is relatively preserved, but memory and cognitive speed decline rapidly. It is important to clarify the cognitive decline of normal aging to evaluate the patients in the early stage of dementia.
In addition, some patients with neurodegenerative disease pathology or traumatic brain injury are cognitively normal in life. These phenomena are considered as "cognitive reserve (CR)", which is associated with a lower risk for cognitive decline.
The present review aims to cover the concept of CR, the past epidemiological studies of CR, the neuroimaging studies of neural basis of CR, and the importance of prevention and non-drug treatment of dementia. |
Keywords |
dementia, cognitive reserve, Alzheimer's disease, neuroimaging, PET |
|