Journal

The Japanese journal of neuropsychology

[Vol.34 No.2 contents]
Japanese/English

Full Text of this Article
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ArticleTitle Dementia and cognitive reserve
Language J
AuthorList Hiroshi Yoshizawa
Affiliation Department of Neurology, Neurological Institute, Tokyo Women's Medical University
Publication Japanese Journal of Neuropsychology: 34 (2), 142-154, 2018
Received
Accepted
Abstract The age-related decline of cognitive function is not homogeneous; vocabulary knowledge is relatively preserved, but memory and cognitive speed decline rapidly. It is important to clarify the cognitive decline of normal aging to evaluate the patients in the early stage of dementia.
In addition, some patients with neurodegenerative disease pathology or traumatic brain injury are cognitively normal in life. These phenomena are considered as "cognitive reserve (CR)", which is associated with a lower risk for cognitive decline.
The present review aims to cover the concept of CR, the past epidemiological studies of CR, the neuroimaging studies of neural basis of CR, and the importance of prevention and non-drug treatment of dementia.
Keywords dementia, cognitive reserve, Alzheimer's disease, neuroimaging, PET

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