Journal

The Japanese journal of neuropsychology

[Vol.34 No.3 contents]
Japanese/English

Full Text of this Article
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ArticleTitle Voxel-based lesion-symptom mapping
Language J
AuthorList Ryuta Kinno
Affiliation Department of Neurology, Showa University Fujigaoka Hospital
Publication Japanese Journal of Neuropsychology: 34 (3), 209-217, 2018
Received
Accepted
Abstract One of the basic approaches in neuropsychology is the thorough examination of the relationship between an identified lesion and patient symptoms. Detailed studies of single cases, such as Tan, HM, and others allow us to model the relationship between the brain and its functional outcomes. However, group studies of patients are often required for assessing the validity of the relationships derived from single case studies. Voxel-based lesion-symptom mapping (VLSM) is a method that can be used to statistically validate such relationships in group studies of patients. However, at the same time, there is a risk of statistical errors in the VLSM analysis in such group studies of patients. Therefore, special attention should be paid while interpreting VLSM results.
Keywords voxel-based lesion-symptom mapping, statistical errors

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