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The Japanese journal of neuropsychology
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Full Text of this Article
in English PDF (146K)
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ArticleTitle
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What Can Acute Aphasia Tell Us About the Brain? |
Language |
E |
AuthorList |
Argye E. Hillis |
Affiliation |
Johns Hopkins University School of Medicine, Johns Hopkins University Department of Cognitive Sciense |
Publication |
Japanese Journal of Neuropsychology: 21 (1), 9-17, 2005 |
Received |
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Accepted |
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Abstract |
Much of what is known about brain/language relationships has been based on observed associations between chronic lesions in a particular area and deficits in particular language tasks. Although this methodology has provided enumerable valuable insights, it also has limitations. In this paper I illustrate some of the limitations of traditional lesion/deficit association studies. I then demonstrate advantages of new twist on lesion/deficit association studies that identifies associations between functionally inactive tissue and deficits in acute stroke that has allowed us to re-evaluate some well accepted hypotheses about brain/language relationships. In addition, I show how this new methodology has provided evidence for neural correlates of very specific cognitive functions underlying language. |
Keywords |
aphasia, stroke, magnetic resonance perfusion weighted imaging |
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