The Japanese journal of neuropsychology

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ArticleTitle	Addition of the cued recall and recognition tasks to Mini Mental State Examination distinguishes aged normal subjects from Alzheimer's disease with mild memory impairment
Language	J
AuthorList	Tomoko Honda¹⁾, Naoaki Ito¹⁾, Atsushi Sato²⁾, Toru Imamura¹⁾³⁾
Affiliation	1) Department of Speech Therapy, School of Health Sciences, Niigata University of Health and Welfare 2) Division of Speech Therapy, Department of Rehabilitation, Niigata Rehabilitation Hospital 3) Department of Neurology, Niigata Rehabilitation Hospital
Publication	Japanese Journal of Neuropsychology: 22 (3), 233-239, 2006
Received	Nov 24, 2005
Accepted	Mar 28, 2006
Abstract	Background: The combined score of free recall, cued recall and recognition tasks using the three word in MMSE is reported to be significantly correlated to the rating of memory impairment in Clinical Dementia Rating (CDR). Objective: To assess the usefulness of the combined score to distinguish aged normal subjects and Alzheimer's Disease (AD) patients with mild memory impairment. Methods: We recruited 31 aged normal subjects and 33 AD patients who were rated as very mild or mild memory impairment in CDR and matched with age and education. Each subject underwent MMSE, and cued recall and recognition tasks for the words which were not recollected in the free recall task in MMSE. Results: For the recent memory impairment, the combined score of free recall, cued recall and recognition tasks showed more than 90% of sensitivity in the AD patients and specificity in the aged normal subjects. Conclusion: The current and previous studies revealed that, the combined score is useful to evaluate both presence or absence and the degree of memory impairment in aged normal subjects and AD patients with mild to moderate impairment.
Keywords	recent memory deficits, cued recall, recognition, Alzheimer's disease (AD), activity of daily living (ADL)