Journal

The Japanese journal of neuropsychology

[Vol.22 No.4 contents]
Japanese/English

Full Text of this Article
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ArticleTitle Closing-in phenomenon in Alzheimer's disease and dementia with Lewy bodies
Language J
AuthorList Erina Yamazaki1), Takuya Sato2), Atsushi Sato2), Yuri Kudou3), Toru Imamura1)3)
Affiliation 1) Department of Speech Therapy, School of Health Sciences, Niigata University of Health and Welfare
2) Division of Speech Therapy, Department of Rehabilitation, Niigata Rehabilitation Hospital
3) Department of Neurology, Niigata Rehabilitation Hospital
Publication Japanese Journal of Neuropsychology: 22 (4), 269-276, 2006
Received Nov 24, 2005
Accepted May 8, 2006
Abstract We examined closing-in phenomenon in consecutive 132 patients with Alzheimer's disease (AD) and 18 patients with Dementia with Lewy bodies (DLB). Each patient underwent the construction tasks in MMSE and Alzheimer's Disease Assessment Scale (ADAS), and the copy task of the Rey's complex figure. Closing-in phenomenon was observed 12 out of 132 AD patients and 6 out of 18 DLB patients. The rate was significantly higher in the DLB group than in the AD group (χ2=8.8, p<.01). Visuocognitive dysfunction is reported to be more profound in DLB when compared with AD. The result of the current study suggests the relation between visuocognitive dysfunction and closing-in phenomenon.
Keywords closing-in phenomenon, Alzheimer's disease, Dementia with Lewy bodies, visuocognitive dysfunction, primitive reflex

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